From Longman Dictionary of Contemporary Englishpiss off phrasal verb spoken not polite1 piss somebody ↔ off to annoy someone very muchThe way she treats me really pisses me off.2 LEAVE A PLACE British English to go away – used especially to tell someone to go awayNow piss off and leave me alone!He pissed off before we got there.3 REFUSE British English used to say no or to refuse to do something → piss→ See Verb table