From Longman Dictionary of Contemporary EnglishBotoxBotox1 trademark a substance that makes muscles relax, which can be injected into the skin around someone's eyes to make the lines disappear and the skin look younger and more attractive Botox injections for wrinklesBotoxBotox2 verb [transitive] trademark to use Botox to remove lines on your face Getting Botoxed is pretty simple. He Botoxed his forehead before the next film.