From Longman Dictionary of Contemporary Englishsomebody’s number is upsomebody’s number is up (also somebody’s number has come up) informal a) used to say that someone will stop being lucky or successful b) used to say that someone will die – used humorously She told her husband she didn’t mind going when her number was up. → number
Examples from the Corpus
somebody’s number is up• This could be the year a lot of politicians find their number is up.• When my number is up, I want it to be quick.• Competition prize winners Kathryn Winkler of Dundee, your lucky number is up. 