From Longman Dictionary of Contemporary Englishfly-by-wireˈfly-by-ˌwire noun [uncountable] a system in an aircraft which uses computers and electrical signals to help control the aircraftFrom Longman Business Dictionaryfly-by-wireˈfly-by-wire adjective [only before a noun] informalCOMPUTING fly-by-wire planes are controlled mainly by computersThe cockpit has digital fly-by-wire controls with an automatic approach and landing system.