Oxford Dictionary English safe sex nounnoun BrE BrE//ˌseɪf ˈseks// ; NAmE NAmE//ˌseɪf ˈseks// [uncountable] Add to my wordlistjump to other resultssexual activity in which people try to protect themselves from AIDS and other sexual diseases, for example by using a condomSee safe sex in the Oxford Advanced American DictionaryCheck pronunciation: safe sex oxfordlearnersdictionaries.com