Oxford Dictionary English main line noun noun BrE BrE//ˌmeɪn ˈlaɪn// ; NAmE NAmE//ˌmeɪn ˈlaɪn// Railway tracks and stations Add to my wordlistjump to other resultsan important railway/railroad line between two cities See related entries: Railway tracks and stationsSee main line in the Oxford Advanced American DictionaryCheck pronunciation: main line oxfordlearnersdictionaries.com