Oxford Dictionary English LSD nounnoun BrE BrE//ˌel es ˈdiː// ; NAmE NAmE//ˌel es ˈdiː// (slang acid) [uncountable] Addiction Add to my wordlistjump to other results a powerful illegal drug that affects people’s minds and makes them see and hear things that are not really there See related entries: Addiction Word Origin1950s: abbreviation.See LSD in the Oxford Advanced American DictionaryCheck pronunciation: LSD oxfordlearnersdictionaries.com