Oxford Dictionary English killer application nounnoun BrE BrE//ˌkɪlər ˌæplɪˈkeɪʃn// ; NAmE NAmE//ˌkɪlər ˌæplɪˈkeɪʃn// (also killer app) (computing) Computer software Add to my wordlistjump to other results a computer program that is so popular that it encourages people to buy or use the operating system, etc. that it runs on See related entries: Computer softwareSee killer application in the Oxford Advanced American DictionaryCheck pronunciation: killer application oxfordlearnersdictionaries.com