From Longman Dictionary of Contemporary Englishset somebody’s teeth on edgeset somebody’s teeth on edgeFEEL HAPPY/FRIGHTENED/BORED ETCif a sound or taste sets your teeth on edge, it gives you an uncomfortable feeling in your mouth a horrible scraping sound that set my teeth on edge → tooth
Examples from the Corpus
set somebody’s teeth on edge• At other times their self-evident frustration sets your teeth on edge.• It was all done so genteelly that it set McAllister's teeth on edge.• That set our teeth on edge and bring our goose pimples rising like porpoises after mackerel.• His high-pitched squeaky voice set my teeth on edge.• He w as filing arrow heads, and the sound of the metal on the whetstone set Burun's teeth on edge.