From Longman Dictionary of Contemporary Englishdepopulatede‧pop‧u‧late /ˌdiːˈpɒpjəleɪt $ -ˈpɑːp-/ verb [transitive] REDUCEto greatly reduce the number of people living in a particular area Disease depopulated the whole region. —depopulation /diːˌpɒpjəˈleɪʃən $ -ˌpɑːp-/ noun [uncountable]
Examples from the Corpus
depopulate• She wants to depopulate the earth and liberate the plants. 