From Longman Dictionary of Contemporary Englishup sticksup sticksBritish English informalLEAVE YOUR HOME/COUNTRY if you up sticks, you move to a different area → stick
Examples from the Corpus
up sticks• Do your homework before applying to permanently up sticks.• He picks up sticks and sits down to eat them.• I couldn't up sticks and away, which I might have done otherwise - regretting it afterwards.• You will then have the right specimens ready and waiting whenever anyone decides to up sticks and move.• Maybe we up sticks and move to another, better part of the country to cool out. 