From Longman Dictionary of Contemporary Englishmanic depressionˌmanic deˈpression noun [uncountable] MPa mental illness that causes someone to feel very strong emotions of happiness and sadness in a short period of time
Examples from the Corpus
manic depression• He still looked rather tired, having spent several weeks in hospital undergoing treatment for manic depression.• The booklet deals with lithium, the drug used for manic depression.• Doctors have treated manic depression with lithium carbonate since the 1970s. 